The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Mar. 17, 2021
Applicant:

Quest Diagnostics Investments Llc, Secaucus, NJ (US);

Inventors:

Maher Albitar, Coto De Caza, CA (US);

Wanlong Ma, Aliso Viejo, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C07H 21/04 (2006.01); C12N 9/12 (2006.01); C12Q 1/6869 (2018.01); C12Q 1/6883 (2018.01); C12Q 1/6886 (2018.01); G01N 33/573 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12N 9/1205 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6883 (2013.01); C12Y 207/10002 (2013.01); G01N 33/573 (2013.01); C12Q 2600/156 (2013.01); G01N 2333/91205 (2013.01); G01N 2800/22 (2013.01); G01N 2800/56 (2013.01);
Abstract

The invention disclosed herein is based on the identification of novel mutations in the JAK2 gene and JAK2 protein. The invention provides compositions and methods useful for diagnosing hematopoietic diseases including, for example, myeloproliferative diseases. The invention also provides compositions and methods useful for determining a prognosis of an individual diagnosed as having a hematopoietic disease.


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