The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Apr. 11, 2019
Applicant:

Life Technologies Corporation, Carlsbad, CA (US);

Inventors:

Maya Yovcheva, Demascus, MD (US);

Jonathan Zmuda, Frederick, MD (US);

Sara Barnes, Germantown, MD (US);

Chang Choi, San Diego, CA (US);

Kenneth Thompson, Burtonsville, MD (US);

Assignee:

Life Technologies Corporation, Carlsbad, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); C12N 5/07 (2010.01); C12N 7/00 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C12N 5/0601 (2013.01); C12N 7/00 (2013.01); C12P 21/00 (2013.01); C12N 2500/02 (2013.01); C12N 2500/05 (2013.01); C12N 2500/34 (2013.01); C12N 2500/38 (2013.01); C12N 2510/00 (2013.01); C12N 2710/14143 (2013.01); C12N 2710/14151 (2013.01);
Abstract

The present disclosure is related generally to systems and methods for high level expression of recombinant proteins from baculovirus in insect cells. In particular, the methods and systems described herein allow for high levels of baculovirus production in insect cells and/or high levels of protein production in insect cells using a chemically-defined, yeast lysate-free insect cell medium. The disclosure also relates to compositions and kits for culturing, transfecting, and/or producing recombinant protein in insect cells.


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