The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2025
Filed:
May. 07, 2019
Pioneer Hi-bred International, Inc., Johnston, IA (US);
Ajith Anand, West Des Monies, IA (US);
William James Gordon-Kamm, Urbandale, IA (US);
Sandeep Kumar, Johnston, IA (US);
Zhan-Bin Liu, Clive, IA (US);
Sergi Svitashev, Johnston, IA (US);
PIONEER HI-BRED INTERNATIONAL, INC., , IA (US);
Abstract
Methods and compositions are provided for the improvement of homology-directed repair of a double strand break in a plant cell, via the use of a polynucleotide comprising sequences homologous to the target site. In some aspects, the double strand break is created by an RNA-guided Cas endonuclease. The homology-directed repair of the double-strand break may include incorporation of a heterologous polynucleotide, for example a gene encoding a trait of agronomic importance. The homology-directed repair of the double-strand break may occur as a result of template-directed repair using a polynucleotide repair template.