The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Oct. 13, 2020
Applicant:

Shanghai University of Medicine&health Sciences, Shanghai, CN;

Inventors:

Gang Huang, Shanghai, CN;

Bin Li, Shanghai, CN;

Yue Li, Shanghai, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/77 (2006.01); C12N 1/00 (2006.01); C12N 1/20 (2006.01); C12N 9/78 (2006.01); C12N 15/66 (2006.01); C12P 13/10 (2006.01); C12R 1/15 (2006.01);
U.S. Cl.
CPC ...
C12N 15/77 (2013.01); C12N 1/005 (2013.01); C12N 1/20 (2013.01); C12N 9/78 (2013.01); C12N 15/66 (2013.01); C12P 13/10 (2013.01); C12Y 305/03006 (2013.01); C07K 2319/735 (2013.01); C12R 2001/15 (2021.05);
Abstract

Arginine deiminase (ADI)-containing genetically engineered(), a fusion protein cipA-arc, use thereof, and a method for preparing [N]-L-citrulline through enzymatic catalysis are provided. The ADI-containing genetically engineered() has a deposit number of CGMCC No. 19404, which expresses a fusion protein cipA-arc. Both the genetically engineered strain and the fusion protein cipA-arc can be used to convert [N]-L-arginine into [N]-L-citrulline.


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