The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Jul. 18, 2023
Applicant:

Oregon State University, Corvallis, OR (US);

Inventors:

Taifo Mahmud, Corvallis, OR (US);

Andrew Robert Osborn, Corvallis, OR (US);

Assignee:

Oregon State University, Corvallis, OR (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/74 (2006.01); A61K 8/40 (2006.01); A61Q 17/04 (2006.01);
U.S. Cl.
CPC ...
C12N 15/74 (2013.01); A61K 8/40 (2013.01); A61Q 17/04 (2013.01); A61K 2800/59 (2013.01);
Abstract

Disclosed is a synthetic gene cluster for producing gadusol derivatives, expression vectors and host cells containing the same, methods of producing gadusol derivatives, and compositions thereof. In an example, the synthetic gene cluster includes a valA nucleotide sequence capable of expressing ValA protein; a nucleotide sequence capable of expressing methyltransferase/oxidoreductase (MT-Ox) protein; a mysC nucleotide sequence capable of expressing a MysC protein; and a mysD nucleotide sequence capable of expressing a MysD protein. In this way, gadusol derivatives can be produced in amounts sufficient for use in a variety of applications.


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