The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2025
Filed:
Aug. 25, 2021
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Julie Horowitz, Tarrytown, NY (US);
Luca Andrea Lotta, Tarrytown, NY (US);
Manuel Allen Revez Ferreira, Tarrytown, NY (US);
Amy Damask, Tarrytown, NY (US);
Charles Paulding, Tarrytown, NY (US);
Garen Manvelian, Tarrytown, NY (US);
Michael Cantor, Tarrytown, NY (US);
Aris Baras, Tarrytown, NY (US);
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Abstract
The present disclosure provides methods of treating subjects having sepsis, SIRS, septic shock, and/or MODS, methods of identifying subjects having an increased risk of developing sepsis, SIRS, septic shock, and/or MODS, and methods of detecting Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and/or Low Density Lipoprotein Receptor (LDLR) variant nucleic acid molecules and variant polypeptides.