The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2025
Filed:
Apr. 13, 2022
Applicant:
Sirnaomics, Inc., Gatithersburg, MD (US);
Inventor:
Dmitry Samarsky, Gaithersburg, MD (US);
Assignee:
Sirnaomics, Inc., Germantown, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 38/36 (2006.01); A61P 7/02 (2006.01); C12N 9/64 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 38/36 (2013.01); A61P 7/02 (2018.01); C12N 9/6443 (2013.01); C12N 2310/11 (2013.01); C12Y 304/21027 (2013.01);
Abstract
Products, compositions, and their uses are provided. In particular, nucleic acid products that modulate, in particular interfere with or inhibit, Factor XI (FXI) gene expression are provided. The products can be oligomeric compounds that comprise at least a first region of linked nucleosides having at least a first nucleobase sequence that is at least partially complementary to at least a portion of RNA transcribed from an FXI gene, wherein said first nucleobase sequence is selected from the following sequences, or a portion thereof: SEQ ID NOs 1 to 250.