The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Apr. 27, 2021
Applicants:

Biontech SE, Mainz, DE;

Tron—translationale Onkologie an Der Universitatsmedizin Der Johannes Gutenberg Universitat Mainz Gemeinnutzige Gmbh, Mainz, DE;

Inventors:

Ugur Sahin, Mainz, DE;

Marco Poleganov, Frankfurt, DE;

Tim Beissert, Griesheim, DE;

Assignee:

BIONTECH SE, Mainz, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0696 (2013.01); C12N 2501/602 (2013.01); C12N 2501/603 (2013.01); C12N 2501/604 (2013.01); C12N 2501/606 (2013.01); C12N 2510/00 (2013.01);
Abstract

Methods for effecting the de-differentiation of somatic cells to cells having stem cell characteristics, in particular pluripotency, include the steps of introducing RNA encoding factors inducing the de-differentiation of somatic cells into the somatic cells and culturing the somatic cells allowing the cells to de-differentiate.


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