The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

May. 17, 2022
Applicant:

Gi Cell, Inc., Gyeonggi-do, KR;

Inventors:

Myoung Ho Jang, Seoul, KR;

Chun-Pyo Hong, Gyeonggi-do, KR;

Dong Woo Ko, Seoul, KR;

June Sub Lee, Gyeonggi-do, KR;

Assignee:

GI CELL, INC., Gyeonggi-Do, KR;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61K 35/17 (2015.01); C07K 14/55 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0646 (2013.01); A61K 35/17 (2013.01); C12N 5/0636 (2013.01); C12N 2501/2302 (2013.01); C12N 2501/51 (2013.01);
Abstract

The invention relates to: a composition for culturing natural killer cells, comprising, as an active ingredient, a fusion protein comprising an IL-2 protein and a CD80 protein; and a method for preparing natural killer cells by using same. Particularly, a composition for culturing natural killer cells, comprising, as an active ingredient, a fusion protein comprising IL-2 or a variant thereof and CD80 or a fragment thereof, of the present invention; promotes the proliferation of natural killer cells, induces the expression of CD16 and NKp46, and increases the expression and secretion of granzyme B and perforin, thereby being effectively usable in the preparation of natural killer cells having an excellent anticancer immune function.


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