The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2025
Filed:
Jul. 28, 2023
Applicant:
Cellphire, Inc., Rockville, MD (US);
Inventors:
Keith Andrew Moskowitz, Westfield, IN (US);
Amber Nicole Lee, Montgomery Village, MD (US);
Rafael Jorda, Merignac, FR;
Assignee:
Cellphire, Inc., Rockville, MD (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C12N 5/078 (2010.01); C12N 15/113 (2010.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0644 (2013.01); C12N 15/113 (2013.01); C12N 15/85 (2013.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12N 2510/00 (2013.01);
Abstract
Provided herein are RNA agent-loaded platelets, methods of preparing RNA agent-loaded platelets, and methods of using RNA agent-loaded platelets. In some embodiments, methods of loading RNA agents into platelets include treating platelets with a RNA agent, a cationic transfection reagent, and a loading buffer that can include a salt, a base, a loading agent, and optionally at least one organic solvent.