The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2025
Filed:
Jul. 21, 2022
Applicants:
Sumitomo Chemical Company, Limited, Tokyo, JP;
Riken, Wako, JP;
Inventors:
Assignees:
SUMITOMO CHEMICAL COMPANY, LIMITED, Tokyo, JP;
RIKEN, Wako, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/079 (2010.01); A61K 35/30 (2015.01); A61L 27/38 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0621 (2013.01); A61K 35/30 (2013.01); A61L 27/3804 (2013.01); A61L 27/3834 (2013.01); A61L 27/3895 (2013.01); A61L 2430/16 (2013.01); C12N 2500/33 (2013.01); C12N 2500/44 (2013.01); C12N 2500/90 (2013.01); C12N 2501/155 (2013.01); C12N 2501/19 (2013.01); C12N 2501/385 (2013.01); C12N 2501/415 (2013.01); C12N 2501/727 (2013.01); C12N 2506/02 (2013.01); C12N 2506/45 (2013.01);
Abstract
The present invention provides a method for producing a retinal progenitor cell, including (1) a first step of subjecting pluripotent stem cells to floating culture in a serum-free medium to form an aggregate of pluripotent stem cells, and (2) a second step of subjecting the aggregate formed in step (1) to floating culture in a serum-free medium or serum-containing medium each being free of a substance acting on the Sonic hedgehog signal transduction pathway but containing a substance acting on the BMP signal transduction pathway, thereby obtaining an aggregate containing retinal progenitor cells.