The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2025
Filed:
Dec. 20, 2023
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventor:
Harald C. Ott, Wenham, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 3/00 (2006.01); A01N 1/00 (2006.01); A01N 1/143 (2025.01); A61K 35/28 (2015.01); A61K 35/36 (2015.01); A61K 35/42 (2015.01); A61K 35/44 (2015.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01); C12M 1/34 (2006.01); C12M 1/36 (2006.01);
U.S. Cl.
CPC ...
C12M 21/08 (2013.01); A01N 1/143 (2025.01); A61K 35/28 (2013.01); A61K 35/36 (2013.01); A61K 35/42 (2013.01); A61K 35/44 (2013.01); C12M 25/14 (2013.01); C12M 29/10 (2013.01); C12M 41/40 (2013.01); C12M 41/44 (2013.01); C12M 41/48 (2013.01);
Abstract
Presented is an airway organ bioreactor apparatus, and methods of use thereof, as well as bioartificial airway organs produced using the methods, and methods of treating subjects using the bioartificial airway organs. The bioreactor comprises: an organ chamber: an ingres line connecting the organ chamber and a reservoir system and comprising an arterial line, a venous line and a tracheal line; an egress line connecting the chamber and the reservoir system, pumps in ingress and egress lines; a controller to control fluid exchange; a chamber pressure sensor connected to the organ chamber.