The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Sep. 19, 2019
Applicants:

Nanyang Technological University, Singapore, SG;

National University of Singapore, Singapore, SG;

Inventors:

Xuewei Liu, Singapore, SG;

Bee Eng Mary Chan, Singapore, SG;

Hongwei Duan, Singapore, SG;

Jingxi He, Singapore, SG;

Kim Le Mai Hoang, Singapore, SG;

Liang Yang, Singapore, SG;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08B 37/00 (2006.01); A61K 47/54 (2017.01); A61K 47/61 (2017.01); A61K 47/64 (2017.01); A61P 31/04 (2006.01); C08B 37/08 (2006.01); C12Q 1/18 (2006.01);
U.S. Cl.
CPC ...
C08B 37/003 (2013.01); A61K 47/542 (2017.08); A61K 47/61 (2017.08); A61K 47/64 (2017.08); A61P 31/04 (2018.01); C12Q 1/18 (2013.01);
Abstract

The invention relates to a compound of formula Ia and/or formula Ib: or a pharmaceutically acceptable salt, solvate or prodrug thereof, where the groups are defined herein. The invention also relates to a pharmaceutical formulation comprising the compound for treating or detecting a microbial infection in a subject, a method of determining antimicrobial resistance of a microbial infection using the compound, and a method of determining an effective dose of one or more antimicrobial agents to kill a microorganism using the compound.


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