The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Aug. 08, 2019
Applicant:

Dragonfly Therapeutics, Inc., Waltham, MA (US);

Inventors:

Gregory P. Chang, Medford, MA (US);

Ann F. Cheung, Lincoln, MA (US);

Jinyan Du, Waltham, MA (US);

Daniel Fallon, Winchester, MA (US);

Asya Grinberg, Lexington, MA (US);

William Haney, Wayland, MA (US);

Bradley M. Lunde, Lebanon, NH (US);

Steven O'neil, Wayland, MA (US);

Bianka Prinz, Lebanon, NH (US);

Ronnie Wei, Weston, MA (US);

Assignee:

DRAGONFLY THERAPEUTICS, INC., Waltham, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2851 (2013.01); A61P 35/00 (2018.01); C07K 16/283 (2013.01); C07K 16/2863 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/52 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/94 (2013.01);
Abstract

Multi-specific binding proteins that bind NKG2D receptor, CD 16, and a tumor-associated antigen selected from c-MET, KIT, F3, IGF1R, Lewis Y, MUC13, MUC4, MCAM, LRRC32, sialyl-Tn, gpA33, GD3, GM2, EPHA3, TNFRSF10A, TNFSF11, CD74, and PMEL are described, as well as pharmaceutical compositions and therapeutic methods useful for the treatment of cancer.


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