The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Apr. 24, 2020
Applicants:

Xuanzhu Biopharmaceutical Co., Ltd., Shijiazhuang, CN;

Beijing Xuanzhu Combio Co., Ltd., Beijing, CN;

Inventors:

Yuntao Song, Palo Alto, CA (US);

Jianhui Zhou, Redwood City, CA (US);

Yi Ding, Milpitas, CA (US);

Ping Hui Szu, Walnut Creek, CA (US);

Chen Dong, Cupertino, CA (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); A61K 38/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70532 (2013.01); A61P 35/00 (2018.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01);
Abstract

The present disclosure provides variant CD80 polypeptides that have altered affinity for their cognate binding partners, and immunomodulatory fusion proteins comprising the variant CD80 polypeptides. The present disclosure also provides pharmaceutical compositions comprising such polypeptides and/or proteins and methods for modulating immune responses and/or treatment of cancer, infectious diseases, and/or immunological diseases.


Find Patent Forward Citations

Song, Yuntao. (2025). Cd80 variant proteins and uses thereof (U.S. Patent No. 12378299). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12378299

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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