The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Apr. 26, 2019
Applicant:

Chiesi Farmaceutici Spa, Parma, IT;

Inventor:
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/48 (2006.01); C07K 1/16 (2006.01); C12N 9/76 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/48 (2013.01); C07K 1/165 (2013.01); C12N 9/6427 (2013.01); A61K 38/00 (2013.01);
Abstract

The present invention relates to a process for production of nerve growth factor (NGF) and muteins thereof, in particular muteins of human NGF. The process of the present invention yields nerve growth factor (NGF) and muteins thereof, e.g. from recombinant sources, at high purity. Aspects related to the process of the present invention, such as muteins obtainable thereby, are also described. The respective muteins may be characterized e.g. by improved detectability and/or reduced nociceptive activity, compared to wildtype human NGF.


Find Patent Forward Citations

Imbimbo, Bruno. (2025). Production of nerve growth factor (ngf) and of muteins thereof (U.S. Patent No. 12378293). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12378293

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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