The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

May. 23, 2019
Applicants:

Cornell University, Ithaca, NY (US);

Memorial Sloan Kettering Cancer Center, New York, NY (US);

Inventors:

Richard Ting, New York, NY (US);

Omer Aras, New York, NY (US);

Feifei An, New York, NY (US);

Nandi Chen, New York, NY (US);

Assignees:

Cornell University, Ithaca, NY (US);

Memorial Sloan Kettering Cancer Center, New York, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61K 9/00 (2006.01); A61M 36/14 (2006.01); C07F 5/02 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01); A61K 9/0019 (2013.01); C07B 2200/05 (2013.01);
Abstract

A compound according to Formula (I) or a pharmaceutically acceptable salt and/or solvate thereof, wherein Xand Xare each independentlyF orF; Rand Rare each independently alkyl, amine, perfluoroalkyl, alkenyl, alkynyl, aryl, or aralkenyl; and Ris H, halo, alkyl, alkyl ester, alkenyl, alkynyl, aryl, or aralkenyl; or wherein: Rand Ror Rand Rjoin to form a 6-membered cycloalkyl or heterocyclyl; or Rand R, Rand R, or R, R, and Rjoin to form a substituted or unsubstituted polycyclic ring, wherein the polycyclic ring comprises fused cycloalkyl, heterocycloalkyl, aryl, or heteroaryl rings.


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