The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2025
Filed:
Apr. 29, 2022
Applicant:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Inventor:
Thomas Nittoli, Pearl River, NY (US);
Assignee:
REGENERON PHARMACEUTICALS, INC., Tarrytown, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 507/00 (2006.01); A61K 31/5365 (2006.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
C07D 507/00 (2013.01); A61K 31/5365 (2013.01); A61K 47/68033 (2023.08); A61K 47/6849 (2017.08); A61K 47/6855 (2017.08); A61K 47/6869 (2017.08); A61K 47/6871 (2017.08);
Abstract
The present disclosure relates to linker compounds that are useful in covalently linking biologically active molecules with Ligands. The disclosed compounds also relate to biologically active molecules and Ligand conjugates, wherein the biologically active molecule is linked to the Ligand through a linker. The disclosure further provides compositions comprising biologically active molecule-ligand conjugates, methods of modifying abnormal cell growth and methods of treatment using the conjugates or the compositions.