The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2025
Filed:
Dec. 06, 2019
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Kenneth A. Jacobson, Silver Spring, MD (US);
Dilip K. Tosh, Rockville, MD (US);
Marc L. Reitman, Potomac, MD (US);
Oksana Gavrilova, Bethesda, MD (US);
Abstract
Disclosed are compounds of the formulas (I), (II), and (II): which are Aadenosine receptor agonists, pharmaceutical compositions comprising such compounds, and a method of use of these compounds, wherein Y, R-R, R-R, and R-Rare as defined in the specification. These compounds are selective to the Aadenosine receptor, and are contemplated for use in the treatment or prevention of a number of diseases or conditions, for example, for inducing and/or maintaining a hypothermic and/or hypometabolic state for treatment of a mammal.