The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Dec. 23, 2022
Applicants:

The Katholieke Universiteit Leuven, Vlaams-Brabant Leuven, BE;

Springworks Therapeutics, Inc., Stamford, CT (US);

Vib Vzw, Ghent, BE;

Inventors:

Bart Vanderhoydonck, Diest, BE;

Arnaud Marchand, Bierbeek, BE;

Aurélie Candi, Werchter, BE;

Matthias Versele, Kessel-Lo, BE;

Assignees:

SPRINGWORKS THERAPEUTICS, INC., Stamford, CT (US);

KATHOLIEKE UNIVERSITEIT LEUVEN, Vlaams-Brabant Leuven, BE;

VIB VZW, Ghent, BE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 223/16 (2006.01); A61K 31/4375 (2006.01); A61K 31/4704 (2006.01); A61K 31/55 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07D 215/227 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 223/16 (2013.01); A61K 31/4375 (2013.01); A61K 31/4704 (2013.01); A61K 31/55 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 215/227 (2013.01); C07D 471/04 (2013.01);
Abstract

The present disclosure relates to novel compounds, to said compounds for use as a medicine, more in particular for the prevention or treatment of diseases mediated by activity of YAP/TAZ-TEAD transcription, yet more in particular for the prevention or treatment of cancer or fibrosis. The present disclosure also relates to a method for the prevention or treatment of said diseases comprising the use of the novel compounds.


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