The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Aug. 17, 2023
Applicant:

Zhejiang University, Zhejiang, CN;

Inventors:

Zhengwei Mao, Zhejiang, CN;

Lisha Yu, Zhejiang, CN;

Weilin Wang, Zhejiang, CN;

Yuan Ding, Zhejiang, CN;

Assignee:

ZHEJIANG UNIVERSITY, Zhejiang, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 24/10 (2006.01); A61L 24/00 (2006.01); A61L 24/02 (2006.01); A61L 24/04 (2006.01); A61L 24/08 (2006.01);
U.S. Cl.
CPC ...
A61L 24/106 (2013.01); A61L 24/0031 (2013.01); A61L 24/02 (2013.01); A61L 24/046 (2013.01); A61L 24/08 (2013.01);
Abstract

The present invention provides a double-crosslinked fibrin gel, which is a solid hydrogel composed of a network structure with a blocking function and a network structure with an adhesion function, where the network structure with the blocking function is a three-dimensional fibrin network, and the network structure with the adhesion function is a three-dimensional photosensitive gel network; each channel of the photosensitive gel network has a group of the fibrin network inside, and each group of the fibrin network has overall continuity; on the whole, the three-dimensional fibrin network disperses disorderly throughout a surface and an interior of the solid hydrogel. The present invention further provides a raw material composition, a kit for preparing the double-crosslinked fibrin gel, and an application of the kit to prepare an in-situ rapid clotting and hemostatic material. The double-crosslinked fibrin gel prepared by the kit has a fast and efficient hemostatic effect, also can be widely applied for hemostasis of accidental trauma or a surgical wound.


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