The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Aug. 23, 2022
Applicant:

University of Washington, Seattle, WA (US);

Inventors:

Miqin Zhang, Seattle, WA (US);

Qingxin Mu, Seattle, WA (US);

Guanyou Lin, Seattle, WA (US);

Assignee:

University of Washington, Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A61K 47/60 (2017.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6929 (2017.08); A61K 47/60 (2017.08); A61K 47/6923 (2017.08); A61P 35/00 (2018.01); A61P 35/04 (2018.01);
Abstract

Multifunctional nanoparticle for targeted therapeutic drug delivery, comprising (a) an iron oxide core having silica-polyethylene glycol coupled thereto to provide an iron oxide coated core, (b) a cytotoxic agent reversibly associated with the coated core; (c) an immunomodulating agent reversibly associate with the coated core; and (d) a tumor targeting agent associated with the coated core. Methods for using the nanoparticle to treat cancers and methods for making the nanoparticle.


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