The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Jul. 31, 2018
Applicants:

Astrazeneca Ab, Sodertalje, SE;

Cambridge Enterprise Limited, Cambridgeshire, GB;

Inventors:

Jeremy Stephen Parker, Macclesfield, GB;

Hannah Fiona Sore, Cambridgeshire, GB;

David Robert Spring, Cambridgeshire, GB;

Stephen James Walsh, Cambridgeshire, GB;

Assignees:

ASTRAZENECA AB, Sodertalje, SE;

CAMBRIDGE ENTERPRISE LIMITED, Cambridge, GB;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61K 31/704 (2006.01); A61K 38/07 (2006.01); A61K 47/54 (2017.01); A61P 35/00 (2006.01); C07D 239/42 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6889 (2017.08); A61K 31/704 (2013.01); A61K 38/07 (2013.01); A61K 47/545 (2017.08); A61K 47/68031 (2023.08); A61K 47/6851 (2017.08); A61P 35/00 (2018.01); C07D 239/42 (2013.01);
Abstract

A conjugate comprising a protein or a peptide, a linker and an active agent, wherein the linker comprises the moiety of formula (III): (III) wherein two of A, Aand Aare N and the other of A, Aand Ais CH; X is selected from N, O and S, and Pep indicates where the moiety is linked to the protein or peptide, either directly or indirectly.


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