The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Mar. 07, 2019
Applicant:

Transgene, Illkirch Graffenstaden, FR;

Inventors:

Karola Rittner, Strasbourg, FR;

Christelle Remy, Lochwiller, FR;

Christine Thioudellet, Strasbourg, FR;

Assignee:

TRANSGENE, Illkirch Graffenstaden, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/29 (2006.01); C07K 14/53 (2006.01); C07K 16/28 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 39/292 (2013.01); A61K 39/00117 (2018.08); C07K 14/53 (2013.01); C07K 16/2878 (2013.01); C12N 15/86 (2013.01); A61K 2039/5256 (2013.01); C12N 2710/20034 (2013.01); C12N 2710/20043 (2013.01);
Abstract

The present invention is in the field of viral immunotherapy. The invention provides new pseudocowpox (PCPV) viruses, in particular recombinant PCPV, composition thereof as well as their therapeutic use for preventing or treating diseases, and, notably, proliferative diseases like cancers and restenosis and infectious diseases such as chronic ones. The present invention also provides methods for generating and amplifying such a PCPV and a method for eliciting or stimulating and/or re-orienting an immune response using such a PCPV. More specifically, the invention provides an alternative to the existing poxvirus vectors such as MVA (Modified Virus Ankara) and may be largely used for the therapeutic vaccination.


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