The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Apr. 01, 2020
Applicant:

Emory University, Atlanta, GA (US);

Inventors:

Lily Yang, Atlanta, GA (US);

Lei Zhu, Atlanta, GA (US);

Assignee:

Emory University, Atlanta, GA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/728 (2006.01); A61K 9/51 (2006.01); A61K 31/437 (2006.01); A61K 47/69 (2017.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/728 (2013.01); A61K 9/5161 (2013.01); A61K 31/437 (2013.01); A61K 47/6939 (2017.08); A61P 35/00 (2018.01);
Abstract

This disclosure relates to hyaluronic acid nanoparticles containing an anticancer agent such as a NADPH oxidase (NOX) inhibitor for targeted delivery to cancerous cells or tumors. In certain embodiments, the nanoparticles are made up of hyaluronic acid conjugated to hydrophobic moieties. In certain embodiments, the hydrophobic moieties are steroid based compounds, such as 5beta-cholanic acid.


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