The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2025
Filed:
Jun. 19, 2020
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Courtney A. Cullis, Bedford, MA (US);
Krista E. Gipson, Medford, MA (US);
Yongbo Hu, Winchester, MA (US);
Shih-Chung Huang, Lexington, MA (US);
Nathanael S. Gray, Jamaica Plain, MA (US);
David A. Scott, Newton, MA (US);
Thomas Gero, Stow, MA (US);
David Heppner, Brookline, MA (US);
Tyler Beyett, Brookline, MA (US);
Ciric To, Medford, MA (US);
Michael Eck, Brookline, MA (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Abstract
The disclosure relates to a compound of Formula (I), which acts as an allosteric inhibitor of epidermal growth factor receptor (EGFR); pharmaceutical compositions comprising the compound; and methods of treating or preventing kinase-mediated disorders, including cancer and other proliferation diseases.