The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Nov. 02, 2020
Applicant:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Steven P. Schwendeman, Superior Township, MI (US);

Jie Tang, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 31/56 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5031 (2013.01); A61K 31/56 (2013.01);
Abstract

The disclosure relates to microspheres comprising a core and a shell. More particularly the disclosure relates to microspheres for extended, controlled release of a poorly water-soluble therapeutic agent having a solubility in water of 50 μg/mL or less, the microsphere having a core comprising the therapeutic agent, and a substantially impermeable shell surrounding the core. Methods of making and using the microspheres are also provided.


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