Synthetic perivascular wrap

Abstract

In one aspect of the present disclosure, devices and methods of treating a vascular anastomosis is disclosed. In one embodiment, the method comprises the steps of: (a) determining the outer diameter of a first vessel to be surgically coupled to a second vessel creating a vascular anastomosis; (b) determining the outer diameter of the second vessel; (c) selecting a perivascular wrap from a plurality of differently sized perivascular wraps such that the perivascular wrap fits around the vascular anastomosis with a constriction of the first vessel of less than 30%; wherein the perivascular wrap includes a shape memory polymer and has at least a first end, a second end, and a medial region; (d) positioning the perivascular wrap onto the first vessel via the first end prior to construction of the vascular anastomosis; (e) coupling the first vessel and the second vessel constructing the vascular anastomosis; and (f) molding the perivascular wrap from a first shape to a second shape wherein the second shape conforms to the geometry of the vascular anastomosis such that the perivascular wrap provides artery-mimetic support to the vascular anastomosis in the range of 0.1-2.0 MPa.