The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2025

Filed:

Nov. 23, 2022
Applicant:

Cedars-sinai Medical Center, Los Angeles, CA (US);

Inventors:

Damini Dey, Los Angeles, CA (US);

Sebastien Cadet, Los Angeles, CA (US);

Piotr Slomka, Los Angeles, CA (US);

Rajendra Makkar, Beverly Hills, CA (US);

Assignee:

CEDARS-SINAI MEDICAL CENTER, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 6/50 (2024.01); A61B 6/00 (2006.01);
U.S. Cl.
CPC ...
A61B 6/504 (2013.01); A61B 6/5217 (2013.01);
Abstract

Calcific and noncalcific aortic tissue components can be quantified. Pre-intervention planning computed tomography angiography imaging data is received. A region of interest is defined between the lower coronary ostium and the virtual basal ring. Cross-sectional images of the region of interest are rendered and calcific and noncalcific tissue components are identified based on Hounsfield unit thresholds. The volumes of the identified calcific and noncalcific tissue components are calculated and used to determine a total tissue volume (e.g., fibrocalcific volume) for the valve, as well as component percentages of the total tissue volume for the calcific and noncalcific components. These volumes and/or component percentages can be leveraged to predict severe AS, identify prognosis of post-TAVI outcomes, or otherwise facilitate planning of medical intervention.


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