The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2025

Filed:

Jul. 29, 2022
Applicant:

The Government of the United States of America, As Represented BY the Secretary of Homeland Security, Washington, DC (US);

Inventors:

Jimmie Oxley, Narragansett, RI (US);

James L. Smith, Narragansett, RI (US);

Alexander Yevdokimov, Norwich, CT (US);

Kevin Colizza, Collegeville, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
H01J 49/00 (2006.01); G01N 30/72 (2006.01); G01N 30/86 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
H01J 49/0036 (2013.01); G01N 30/7233 (2013.01); G01N 30/8631 (2013.01); G01N 30/8693 (2013.01); G01N 30/8696 (2013.01); G01N 2030/027 (2013.01);
Abstract

Examples are directed toward collecting, by a LC-MS device, a full scan of ion chromatograms of a sample. The LC-MS device determines observed ions contained in the full scan, based on mass-to-charge ratios (m/z), and determines, for a formation curve of an observed ion, a formation point at which fifty percent of the observed ion has formed. The LC-MS device determines a fragmentation curve of a precursor ion, based on a fragmentation point of the fragmentation curve equivalent to the formation point at which fifty percent of the precursor ion has fragmented, and identifies the precursor ion by referencing the LC-MS library to confirm that the observed ion is a product of the fragmentation of the precursor ion. The LC-MS device indicates a goodness of fit between the fragmentation curve, as observed, and a model fragmentation curve, as stored in the LC-MS library.


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