The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2025
Filed:
Jun. 27, 2018
Applicants:
The Broad Institute, Inc., Cambridge, MA (US);
The General Hospital Corporation, Boston, MA (US);
Inventors:
Ramnik Xavier, Boston, MA (US);
Daniel B. Graham, Cambridge, MA (US);
Chengwei Luo, Cambridge, MA (US);
Assignees:
THE BROAD INSTITUTE, INC, Cambridge, MA (US);
THE GENERAL HOSPTIAL CORPORATION, Boston, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G16B 20/30 (2019.01); A61K 39/00 (2006.01); A61K 39/02 (2006.01); C07K 14/195 (2006.01); G16B 15/30 (2019.01); G16B 35/20 (2019.01); G16B 40/20 (2019.01);
U.S. Cl.
CPC ...
G16B 20/30 (2019.02); A61K 39/0208 (2013.01); C07K 14/195 (2013.01); G16B 15/30 (2019.02); G16B 35/20 (2019.02); G16B 40/20 (2019.02); A61K 2039/57 (2013.01); A61K 2039/605 (2013.01);
Abstract
A system and method for prediction of immunodominant epitopes is provided herein. MHCII peptidomics was used to discover complex bacterial epitopes and host antigen processing pathways. Novel insights into the features of antigenicity are leveraged to build an algorithm for prediction of immunodominant epitopes. Use of immunodominant epitopes is described.