The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2025
Filed:
Jun. 28, 2019
Curevac Manufacturing Gmbh, Tübingen, DE;
Tesla Automation Gmbh, Prüm, DE;
Benyamin Yazdan Panah, Tübingen, DE;
Tilmann Roos, Tübingen, DE;
Martin Kunze, Tübingen, DE;
Felix Bertsch, Tübingen, DE;
Aniela Wochner, Tübingen, DE;
Michael Rauen, Tübingen, DE;
Philipp Hoffmann, Tübingen, DE;
CureVac Manufacturing GmbH, Tübingen, DE;
Tesla Automation GmbH, Prüm, DE;
Abstract
The present invention relates to a bioreactor for RNA in vitro transcription, a method for RNA in vitro transcription, a module for transcribing DNA into RNA and an automated apparatus for RNA manufacturing. Further, the use of a bioreactor for RNA in vitro transcription as described herein is part of the present invention. The present invention relates to an RNA in vitro transcription reactor designed to be operable in an automated manner under GMP-compliant conditions. In particular, said RNA in vitro transcription reactor allows repetitive use of DNA template for various RNA in vitro transcription reactions. Further, the invention relates to an apparatus for RNA manufacturing comprising (a) a module for template DNA synthesis, (b) a module for transcribing DNA into RNA comprising said RNA in vitro transcription reactor, and, optionally, (c) a module for RNA formulation.