The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2025

Filed:

Oct. 09, 2024
Applicants:

University of Tsukuba, Tsukuba, JP;

Tnax Biopharma Corporation, Tsukuba, JP;

Inventors:

Akira Shibuya, Tsukuba, JP;

Kazuko Shibuya, Tsukuba, JP;

Yumi Kanemaru, Cambridge, GB;

Fumie Abe, Tsukuba, JP;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); C12N 15/63 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); C07K 2317/71 (2013.01);
Abstract

One aspect of the present invention is a humanized anti-DNAM-1 antibody or an antigen-binding fragment thereof, including: a heavy chain variable region containing an amino acid sequence of SEQ ID NO: 1 as HCDR1, an amino acid sequence of SEQ ID NO: 2 as HCDR2, and an amino acid sequence of SEQ ID NO: 3 as HCDR3; and a light chain variable region containing an amino acid sequence of SEQ ID NO: 4 as LCDR1, an amino acid sequence of SEQ ID NO: 5 as LCDR2, and an amino acid sequence of SEQ ID NO: 6 as LCDR3.


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