The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2025

Filed:

Jan. 22, 2019
Applicant:

Clemson University Research Foundation, Clemson, SC (US);

Inventors:

Narendra R. Vyavahare, Clemson, SC (US);

Charles D. Rice, Clemson, SC (US);

Nasim Nosoudi, Clemson, SC (US);

Saketh Karamched, Clemson, SC (US);

Vaideesh Parasaram, Clemson, SC (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 47/68 (2017.01); A61K 49/00 (2006.01); C07K 14/78 (2006.01); C07K 16/18 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 39/3955 (2013.01); A61K 47/6843 (2017.08); A61K 49/0058 (2013.01); C07K 14/78 (2013.01); G01N 33/53 (2013.01); G01N 33/6887 (2013.01); A61K 2039/505 (2013.01); G01N 2333/78 (2013.01);
Abstract

Antibodies and antigen binding fragments thereof that specifically recognize and bind an epitope of elastin that is exposed and accessible in degraded elastic fiber are described. The antibodies and/or antigen binding fragments can be operably linked to a secondary component, including biologically active agents such as therapeutics and/or imaging agents. Optionally, the antibodies and/or antigen binding fragments thereof can be attached to a surface of a carrier, such as a particle, for specific binding and delivery of the carried agents to degraded elastic fiber.


Find Patent Forward Citations

Loading…