The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2025

Filed:

Nov. 10, 2022
Applicant:

Institute of Animal Sciences of Chinese Academy of Agricultural Sciences, Beijing, CN;

Inventors:

Hong Jia, Beijing, CN;

Hongfei Zhu, Beijing, CN;

Weifeng Yuan, Beijing, CN;

Shaohua Hou, Beijing, CN;

Xiaoyu Guo, Beijing, CN;

Yitong Jiang, Beijing, CN;

Qianqian Feng, Beijing, CN;

Zhaoyang Wang, Beijing, CN;

Ting Xin, Beijing, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/08 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C07K 16/081 (2013.01); C12N 15/86 (2013.01); C07K 2317/14 (2013.01); C07K 2317/569 (2013.01); C07K 2317/76 (2013.01); C12N 2750/14323 (2013.01); C12N 2750/14334 (2013.01); C12N 2750/14343 (2013.01); C12N 2750/14352 (2013.01); C12N 2750/14362 (2013.01);
Abstract

A heavy-chain variable region sequence of the nanobody CPV-VHH-H1 has the amino acid sequence set forth in SEQ ID NO: 1; and a gene encoding the nanobody CPV-VHH-H1 has the nucleotide sequence set forth in SEQ ID NO: 2. A nanobody immune library of the CPV is constructed by a phage display technology, a specific anti-CPV nanobody CPV-VHH-H1 is obtained by screening, and it is verified by experiments that the nanobody may specifically bind to the CPV. A new nanobody preparation for use in clinical diagnosis and treatment of the CPV can be developed, and a certain theoretical reserve is provided for applying the nanobody to the field of veterinary biological products.


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