The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2025

Filed:

Apr. 19, 2022
Applicants:

New York University, New York, NY (US);

Cornell University, Ithaca, NY (US);

Inventors:

Paramjit S. Arora, Cold Spring Harbor, NY (US);

Ethel Cesarman, Jersey City, NJ (US);

Michael G. Wuo, Brooklyn, NY (US);

Jouliana Sadek, Roosevelt Island, NY (US);

Assignees:

NEW YORK UNIVERSITY, New York, NY (US);

CORNELL UNIVERSITY, Ithaca, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 47/65 (2017.01); A61P 35/00 (2006.01); C07C 49/04 (2006.01); C07K 7/02 (2006.01); C07K 7/08 (2006.01); C07K 14/47 (2006.01); A61K 38/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4702 (2013.01); A61K 47/65 (2017.08); A61P 35/00 (2018.01); C07C 49/04 (2013.01); C07K 7/02 (2013.01); C07K 7/08 (2013.01); A61K 38/00 (2013.01); A61K 45/06 (2013.01);
Abstract

This invention relates to macrostructures (and pharmaceutical formulations containing them) that include a parallel coiled-coil structure, wherein the parallel coiled-coil comprises a first coil of Formula I and a second coil of Formula II:T-f-g-a-b-c-d-e-f-g-a-b-c-d-e-f-g-a-b-c-d-e-T  (I)T-g'-a′-b′-c′-d′-e′-f′-g′-a′-b′-c′-d′-e′-f′-g′-a′-b′-c′-d′-e′-f′-T  (II),as described in the present application. Methods of using these macrostructures are also disclosed.


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