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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12371454 B1

PDFFull Text
Date of Patent:
Jul. 29, 2025

Filed:

Jul. 15, 2024

Cyclic peptide compound having kras inhibitory action

Applicant:

Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;

Inventors:

Mikimasa Tanada, Gotemba, JP;

Koji Takano, Kamakura, JP;

Atsushi Matsuo, Kamakura, JP;

Minoru Tamiya, Gotemba, JP;

Aya Chiyoda, Gotemba, JP;

Toshiya Ito, Gotemba, JP;

Takeo Iida, Singapore, SG;

Assignee:

CHUGAI SEIYAKU KABUSHIKI KAISHA, Tokyo, JP;

Attorney:

Nixon & Vanderhye P.C.

Primary Examiner:

Aradhana Sasan

Assistant Examiner:

Mercy H Sabila

Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07C 271/22 (2006.01); C07C 317/04 (2006.01); C07C 323/09 (2006.01); C07D 205/04 (2006.01); C07D 211/38 (2006.01); C07D 213/55 (2006.01); C07D 213/61 (2006.01); C07D 213/64 (2006.01); C07D 213/65 (2006.01); C07D 295/15 (2006.01); C07D 309/12 (2006.01); C07D 333/28 (2006.01); C07D 409/12 (2006.01); C07F 5/02 (2006.01); C07K 7/64 (2006.01);
U.S. Cl.
CPC ...
C07K 7/64 (2013.01); C07C 271/22 (2013.01); C07C 317/04 (2013.01); C07C 323/09 (2013.01); C07D 205/04 (2013.01); C07D 211/38 (2013.01); C07D 213/55 (2013.01); C07D 213/61 (2013.01); C07D 213/64 (2013.01); C07D 213/65 (2013.01); C07D 295/15 (2013.01); C07D 309/12 (2013.01); C07D 333/28 (2013.01); C07D 409/12 (2013.01); C07F 5/025 (2013.01); A61K 38/00 (2013.01); C07C 2601/02 (2017.05); C07C 2601/04 (2017.05); C07C 2601/08 (2017.05); C07C 2603/18 (2017.05);
Abstract

The present inventors found cyclic peptide compounds that interact with Ras, and non-natural amino acids useful for the production of the cyclic peptide compounds. The inventors also found that the cyclic peptide compounds inhibit the binding between Ras and SOS. In addition, the inventors found specific non-natural amino acids contained in the cyclic peptide compounds and methods for production thereof.

Find Patent Forward Citations

Tanada, Mikimasa. (2025). Cyclic peptide compound having kras inhibitory action (U.S. Patent No. 12371454). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12371454

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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