The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2025
Filed:
Oct. 29, 2019
Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Lianyungang, CN;
Fei Liu, Lianyungang, CN;
Weiwei Feng, Lianyungang, CN;
Bin Wang, Lianyungang, CN;
Hongjiang Xu, Lianyungang, CN;
Jinan Wang, Lianyungang, CN;
Xiquan Zhang, Lianyungang, CN;
Shanchun Wang, Lianyungang, CN;
Yanlong Liu, Lianyungang, CN;
Jianqing Zhang, Lianyungang, CN;
Yiyan Yao, Lianyungang, CN;
Xujing Tang, Lianyungang, CN;
Wei Shi, Lianyungang, CN;
Hongying Zhang, Lianyungang, CN;
Yang Li, Lianyungang, CN;
Song Tang, Lianyungang, CN;
Yizhong Zhu, Lianyungang, CN;
Limin Liu, Lianyungang, CN;
Hongmei Gu, Lianyungang, CN;
Ling Yang, Lianyungang, CN;
Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Lianyunggang, CN;
Abstract
Disclosed is a trifluoromethyl-substituted sulfonamide BCL-2-selective inhibitor, in particular disclosed are a compound of formula I, a stereoisomer or a pharmaceutically acceptable salt thereof, a preparation method therefor, and a pharmaceutical composition thereof. Also disclosed are the uses of said compound and of a pharmaceutical composition comprising same for treating anti-apoptotic BCL-2-related diseases, such as cancer.