The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2025

Filed:

Mar. 29, 2021
Applicant:

Ustav Organicke Chemie a Biochemie Av Cr, V. V. I., Prague, CZ;

Inventors:

Adela Simkova, Prague, CZ;

Pavel Sacha, Prague, CZ;

Natan Sidej, Prague, CZ;

Tereza Ormsby, Prague, CZ;

Jan Konvalinka, Prague, CZ;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); A61P 35/00 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61P 35/00 (2018.01); C07D 401/14 (2013.01);
Abstract

Quinolinecarboxamide compounds of general formula I exceed the previously known FAP inhibitors in affinity and inhibitory effect. These agents can be used to specifically target tumours for diagnostic and therapeutic purposes, or for laboratory purposes in the study of endogenous FAP expression.


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