The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2025

Filed:

Oct. 26, 2023
Applicant:

Novatarg, Inc., Research Triangle Park, NC (US);

Inventors:

Kenneth Batchelor, Wilmington, NC (US);

Jeffery E. Cobb, Chapel Hill, NC (US);

Kristjan S. Gudmundsson, Raleigh, NC (US);

Brad R. Henke, Cary, NC (US);

Francis X. Tavares, Durham, NC (US);

Assignee:

NovaTarg, Inc., Research Triangle Park, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/20 (2006.01); A61P 3/10 (2006.01); C07D 209/32 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 209/20 (2013.01); A61P 3/10 (2018.01); C07D 209/32 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention provides novel fused bicyclic alkylene linked imidodicarbonimidic diamides. In particular, described herein are N-[2-(indol-3-yl)alkylene]-linked imidodicarbonimidic diamides and N-[2-(pyrrolopyridin-3-yl)alkylene]-linked imidodicarbonimidic diamides (compound of formula (I) or formula (II)), and uses therefor. The compounds of the present invention are believed to be organic cation transporter selective compounds, useful for the treatment of diseases and conditions caused by reduced activity of 5' adenosine monophosphate-activated protein kinase (AMPK).


Find Patent Forward Citations

Batchelor, Kenneth. (2025). Fused bicyclic alkylene linked imidodicarbonimidic diamides, methods for synthesis, and uses in therapy (U.S. Patent No. 12371404). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12371404

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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