The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2025

Filed:

May. 18, 2022
Applicant:

2pi-sigma Corp., Newport Beach, CA (US);

Inventor:

Mehdi Hatamian, Mission Viejo, CA (US);

Assignee:

2Pi-Sigma Corp., Newport Beach, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01L 9/00 (2006.01); G01N 27/327 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); B01L 9/52 (2013.01); G01N 27/3275 (2013.01); G01N 33/54388 (2021.08); B01L 2200/026 (2013.01); B01L 2200/16 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/069 (2013.01); B01L 2300/0825 (2013.01); B01L 2400/0406 (2013.01); G01N 2333/70596 (2013.01);
Abstract

A lateral flow assay device comprises a test strip to receive a quantity of fluid comprising a quantity of exosomes and detect the presence of a target analyte on the surface of the exosomes. The test strip comprises a conjugate pad that contains a set of one or more types of tetraspanin binding reagents conjugated with a label. Each type of tetraspanin binding reagent is configured to bind with a corresponding type of exosome tetraspanin and form an immunocomplex comprising an exosome. The conjugate pad is fluidly connected to a membrane. The membrane comprises a test line comprising an immobilized binding reagent to the target analyte. The immobilized binding reagent to the target analyte is configured to bind to a protein of the target analyte on the surface of an exosome in an immunocomplex comprising the exosome.


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