The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2025

Filed:

Oct. 18, 2022
Applicants:

Varian Medical Systems, Inc.;

Aarhus University, Aarhus, DK;

Central Denmark Region, Viborg, DK;

Inventors:

Ricky Anupam Sharma, Palo Alto, CA (US);

Sophia Pfister, Redwood City, CA (US);

Marta Vilalta, Palo Alto, CA (US);

Brita Singers Sørensen, Aarhus, DK;

Per Rugaard Poulsen, Aarhus, DK;

Gael Luis Boivin, Zurich, CH;

Assignees:

Varian Medical Systems, Inc., Palo Alto, CA (US);

Aarhus University, Aarhus C, DK;

Central Denmark Region, Viborg, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
A61N 5/10 (2013.01); A61N 2005/1087 (2013.01);
Abstract

The present disclosure relates to the field of radiotherapy, in particular, methods of and apparatus for treating cancer using ultra-high dose rate radiotherapy (FLASH). The apparatus may comprise a device configured to administer to the subject no more than five fractions of proton ultra-high dose rate radiotherapy (FLASH), said fractions having a range of radiation from 1.5 Gy to 60 Gy, collectively. The device may be configured such that the treatment is sufficient to prevent further growth of the tumor for at least 10% longer than standard of care radiotherapy, induce at least 10% more tumor regression than standard of care radiotherapy and/or delay tumor regrowth by at least about 2 months longer than standard of care radiotherapy.


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