The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2025
Filed:
Mar. 28, 2022
Applicant:
Translate Bio, Inc., Lexington, MA (US);
Inventors:
Shrirang Karve, Lexington, MA (US);
Zarna Patel, Lexington, MA (US);
Ashish Sarode, Lexington, MA (US);
Yi Zhang, Lexington, MA (US);
Frank Derosa, Lexington, MA (US);
Michael Heartlein, Lexington, MA (US);
Assignee:
Translate Bio, Inc., Lexington, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/00 (2006.01); A61K 31/7105 (2006.01); A61K 47/54 (2017.01); A61K 47/64 (2017.01); A61K 47/69 (2017.01); C12N 15/63 (2006.01); C12N 15/85 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6455 (2017.08); A61K 31/7105 (2013.01); A61K 47/555 (2017.08); A61K 47/6929 (2017.08); C12N 15/85 (2013.01); A61K 2039/51 (2013.01);
Abstract
The present invention provides, among other things, methods and compositions of formulating nucleic acid-containing nanoparticles for efficient delivery of payload in vivo such that the method and compositions can be used to generate mRNA vaccines.