The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2025

Filed:

Apr. 06, 2022
Applicant:

Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);

Inventors:

Sahar Gelfman, Tarrytown, NY (US);

Ann Ligocki, Tarrytown, NY (US);

Giovanni Coppola, Tarrytown, NY (US);

Aris Baras, Tarrytown, NY (US);

Arden Moscati, Tarrytown, NY (US);

Eli A. Stahl, Tarrytown, NY (US);

Jack A. Kosmicki, Tarrytown, NY (US);

Manuel Allen Revez Ferreira, Tarrytown, NY (US);

Carmelo Romano, Tarrytown, NY (US);

Assignee:

Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 31/713 (2006.01); C07K 16/28 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 31/713 (2013.01); C07K 16/2833 (2013.01); C07K 16/40 (2013.01);
Abstract

The present disclosure provides methods of treating subjects having an immune disorder by administering to the subject a therapeutically effective amount of an Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) inhibitor in combination with an HLA-A29 or HLA-B27 inhibitory nucleic acid molecule.


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