The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2025
Filed:
Oct. 21, 2020
Applicant:
University of Manitoba, Winnipeg, CA;
Inventor:
Xiao-Jian Yao, Winnipeg, CA;
Assignee:
University of Manitoba, Winnipeg, CA;
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/005 (2006.01); A61K 39/00 (2006.01); A61K 39/145 (2006.01); A61K 39/295 (2006.01); A61P 37/04 (2006.01); C07K 14/11 (2006.01);
U.S. Cl.
CPC ...
A61K 39/295 (2013.01); A61K 39/145 (2013.01); A61P 37/04 (2018.01); C07K 14/005 (2013.01); A61K 2039/5258 (2013.01); C07K 2319/00 (2013.01); C12N 2760/14122 (2013.01); C12N 2760/14134 (2013.01); C12N 2760/16122 (2013.01); C12N 2760/16134 (2013.01);
Abstract
We have recently developed a novel DC-targeting vaccine platform using Ebola glycoprotein (EboGP) DC-targeting domain-based fusion protein technology. Here, we will use this technology to generate universal vaccines against Influenza A by fusing a DC-targeting/activation domain (EboGPAM), derived from EboGP to I) a tetrameric conserved extracellular domain of M2 (M2e) of Influenza A strains from human, birds, and swine; 2) the conserved stalk regions (HAcs) of HA and an M2 polypeptide from H5N1 strain; and 3) the HA head regions polypeptides (HA) derived from H5N1, H1 N1 and H3N2 strains.