The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2025
Filed:
Feb. 25, 2021
Applicant:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Inventors:
Irving L. Weissman, Stanford, CA (US);
Judith A. Shizuru, Palo Alto, CA (US);
Akanksha Chhabra, San Francisco, CA (US);
Benson M. George, Palo Alto, CA (US);
Assignee:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 35/28 (2015.01); A61K 39/395 (2006.01); A61P 37/06 (2006.01); C07K 16/28 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 39/001 (2013.01); A61K 39/39541 (2013.01); A61P 37/06 (2018.01); C07K 16/2803 (2013.01); C07K 16/2866 (2013.01); C07K 16/2875 (2013.01); A61K 2035/122 (2013.01); A61K 2039/505 (2013.01);
Abstract
The present invention provides a clinically applicable method of stem cell transplantation that facilitates engraftment and reconstitutes immunocompetence of the recipient without requiring radiotherapy or chemotherapy, and without development of GVHD or graft rejection.