The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2025

Filed:

Jun. 02, 2023
Applicant:

Maco Pharma, Mouvaux, FR;

Inventors:

Bruno Delorme, Marcq-en-Baroeul, FR;

Sabrina Viau, Wasquehal, FR;

Francis Goudaliez, Faches-Thumesnil, FR;

Assignee:

Maco Pharma, Mouvaux, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/19 (2015.01); A61L 2/00 (2006.01); C12N 5/0775 (2010.01); C12N 5/078 (2010.01);
U.S. Cl.
CPC ...
A61K 35/19 (2013.01); A61L 2/0035 (2013.01); C12N 5/0644 (2013.01); C12N 5/0662 (2013.01); C12N 2500/84 (2013.01); C12N 2501/115 (2013.01); C12N 2529/00 (2013.01);
Abstract

A sterilised platelet lysate obtained with a method for sterilising a platelet lysate in the liquid state comprising at least the endogenous growth factors TGF-beta 1, EGF, PDGF-AB, IGF-1, VEGF and bFGF. The method comprising freezing the liquid platelet lysate in order to obtain a frozen platelet lysate, and irradiating the frozen platelet lysate with ionising radiation in order to obtain a sterilised platelet lysate, the irradiation being adapted so as to preserve at least 80% of the concentration of at least one of the endogenous growth factors chosen from the group consisting of TGF-beta 1, EGF, PDGF-AB, IGF-1 and VEGF.


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