The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2025

Filed:

May. 13, 2020
Applicant:

Htyr Acquistion Llc, Philadelphia, PA (US);

Inventors:

Yosef Refaeli, Denver, CO (US);

Brian C. Turner, Denver, CO (US);

Thomas R. Payne, Aurora, CO (US);

Assignee:

HTYR Acquisition LLC, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2025.01); A61K 35/15 (2025.01); A61K 35/18 (2015.01); A61K 39/00 (2006.01); A61K 39/04 (2006.01); A61K 39/12 (2006.01); A61K 39/39 (2006.01); A61K 40/10 (2025.01); A61K 40/42 (2025.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/18 (2013.01); A61K 35/17 (2013.01); A61K 39/00 (2013.01); A61K 39/001152 (2018.08); A61K 39/04 (2013.01); A61K 39/12 (2013.01); A61K 39/39 (2013.01); A61K 40/10 (2025.01); A61K 40/4242 (2025.01); A61P 35/00 (2018.01); A61K 2239/31 (2023.05); C12N 2740/16334 (2013.01);
Abstract

Provided herein are compositions and methods for treating T cell exhaustion in a subject, by administering a PTD-MYC fusion protein (e.g., an HIV TAT-MYC fusion protein) or immune cells treated with a PTD-MYC fusion protein. Kits for use in practicing the methods are also provided herein.


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