The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2025
Filed:
Jul. 30, 2020
Ascentage Pharma (Suzhou) Co., Ltd., Suzhou, CN;
Ascentage Pharma Group Corp Limited, Hong Kong, CN;
Dajun Yang, Suzhou, CN;
Yifan Zhai, Suzhou, CN;
Douglas Dong Fang, Suzhou, CN;
Qiuqiong Tang, Suzhou, CN;
ASCENTAGE PHARMA (SUZHOU) CO., LTD., Jiangsu, CN;
ASCENTAGE PHARMA GROUP CORP LIMITED, Hong Kong, CN;
Abstract
Provided herein is a combination product comprising a Bcl-2/Bcl-xL inhibitor and a chemotherapeutic agent, in particular a Bcl-2/Bcl-xL inhibitor of formula (I-A) and homoharringtonine or an active derivative thereof, in free or pharmaceutically acceptable salt or solvate form. Provided herein is also the use of the aforementioned combination for the preparation of a medicament for the prevention and/or treatment of cancer, in particular of hematological malignancies, and to a method for the prevention and/or treatment of cancer, in particular of hematological malignancies, using the aforementioned combination.