The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2025

Filed:

Oct. 08, 2024
Applicant:

Cytokinetics, Inc., South San Francisco, CA (US);

Inventors:

Fady Malik, Burlingame, CA (US);

Stuart Kupfer, Highland Park, IL (US);

Stephen B. Heitner, Portland, OR (US);

Laura Ann Robertson, San Francisco, CA (US);

Lixin Meng, Cupertino, CA (US);

Anna Osmukhina, Portland, OR (US);

Qi Wohltman, Belmont, CA (US);

Assignee:

CYTOKINETICS, INC., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4245 (2006.01); A61P 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4245 (2013.01); A61P 9/00 (2018.01);
Abstract

Methods for treating obstructive hypertrophic cardiomyopathy are described herein. The treatment methods include the administration of a cardiac myosin inhibitor (CK-3773274, also referred to as CK-274 or aficamten) and may include titrating an administrated daily dose based on one or more components of an echocardiogram. The daily dose may be increased, maintained, decreased, or terminated, based on the echocardiogram.


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